The Solomon H. Snyder Department of Neuroscience
Johns Hopkins University
School of Medicine
Dept. of Neuroscience
725 N. Wolfe St.
Baltimore, MD 21205
Room: 908 Wood Basic Science Building
Dr. Dong, trained in molecular neuroscience, has identified many genes specifically expressed in primary sensory neurons in dorsal root ganglia (DRG). He is interested in studying the function of these genes in pain and itch sensation by multiple approaches including molecular biology, mouse genetics, mouse behavior, and electrophysiology.
The laboratory will use these genes as molecular tools to understand the cellular properties of different subtypes of DRG neurons with respect to neuronal circuitry in central projection and pain and itch modalities. The laboratory also is investigating the molecular mechanism of how skin mast cells sensitize sensory nerves under inflammatory states.