Michael Caterina, M.D., Ph.D.

Professor of Biological Chemistry
Johns Hopkins University School of Medicine

JHU School of Medicine
725 N. Wolfe St. 408 Biophysics Building
Baltimore, MD21205
Office Phone: 410-502-5457
Lab Phone: 410-614-1230
Fax: 410-955-5759

Research summary

Dr. Caterina’s laboratory studies the mechanisms for detecting, transmitting and perceiving thermal sensations and pain. Using molecular genetic and behavioral approaches, his group has established the role of mammalian Transient Receptor Potential (TRP) family of channels in thermosensation. These channels, first identified by Dr Caterina when he was a postdoctoral fellow, are responsible for the >pungency of hot peppers, painful heat as well as the cooling sensation on menthol. Currently his lab is elucidating the roles of temperature-gated TRP channels in nonneuronal cells such as skin keratinocytes; and a novel form of activity-dependent plasticity in TRP channel signaling.

Caterina Lab